Invention Grant
- Patent Title: Azaquinazoline inhibitors of atypical protein kinase C
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Application No.: US14975605Application Date: 2015-12-18
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Publication No.: US09896446B2Publication Date: 2018-02-20
- Inventor: Henry J. Breslin , Bruce D. Dorsey , Benjamin J. Dugan , Robert L. Hudkins , Eugen F. Mesaros , Gregory R. Ott , Craig A. Zificsak , Allison L. Zulli , Ming Tao , Katherine M. Fowler , Emma L. Morris , Gregoire A. Pave , Jonathan R. A. Roffey , Nathaniel J. T. Monck , Christelle N. Soudy , Ikeoluwa Olowoye
- Applicant: IGNYTA, INC. , Cancer Research Technology Limited
- Applicant Address: GB London
- Assignee: CANCER RESEARCH TECHNOLOGY LIMITED
- Current Assignee: CANCER RESEARCH TECHNOLOGY LIMITED
- Current Assignee Address: GB London
- Agency: Foley & Lardner LLP
- Main IPC: A61K31/407
- IPC: A61K31/407 ; C07D471/04 ; C07D519/00 ; C07D493/08 ; C07D498/04 ; C07F9/6584
Abstract:
The present application provides a compound of formula (I) or a salt thereof, wherein R7, R8, R9, G, and X are as defined herein. This application further describes compositions comprising the same. Compounds of formula (I) and their salts have aPKC inhibitory activity, and may be used to treat proliferative diseases.
Public/Granted literature
- US20160102094A1 Azaquinazoline Inhibitors of Atypical Protein Kinase C Public/Granted day:2016-04-14
Information query
IPC分类:
