- 专利标题: Detection of single nucleotide polymorphisms in human KRAS
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申请号: US14748155申请日: 2015-06-23
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公开(公告)号: US09909187B2公开(公告)日: 2018-03-06
- 发明人: Shiaolan Y. Ho , Ankur H. Shah , Xiaodi Chen
- 申请人: Abbott Molecular Inc.
- 申请人地址: US IL Des Plaines
- 专利权人: Abbott Molecular Inc.
- 当前专利权人: Abbott Molecular Inc.
- 当前专利权人地址: US IL Des Plaines
- 代理机构: Michael Best & Friedrich LLP
- 代理商 Lisa V. Mueller
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C12P19/34 ; C07H21/02 ; C07H21/04
摘要:
Disclosed herein are primers and probes for the detection of single nucleotide polymorphisms (SNPs) in the KRAS gene. These primers and probes may be used in a method of identifying the presence or absence of one or more SNPs in the KRAS gene. These primers and probes may also be used in a method of predicting a response of a subject in need thereof to a cancer therapy. The primers and probes may further be used in a method of selecting a cancer therapy for a subject in need thereof.
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