Invention Grant
- Patent Title: Isothermal amplification using oligocation-conjugated primer sequences
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Application No.: US15177149Application Date: 2016-06-08
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Publication No.: US09920359B2Publication Date: 2018-03-20
- Inventor: Ryan Charles Heller , John Richard Nelson
- Applicant: General Electric Company
- Applicant Address: US NY Schenectady
- Assignee: GENERAL ELECTRIC COMPANY
- Current Assignee: GENERAL ELECTRIC COMPANY
- Current Assignee Address: US NY Schenectady
- Agent Pabitra K. Chakrabarti
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07H21/04 ; C12N9/00
Abstract:
Provided herein are methods and kits for isothermal nucleic acid amplifications that use an oligocation-oligonucleotide conjugate primer for amplifying a target nucleic acid to generate amplicons. Isothermal DNA amplification methods that employ a strand displacing DNA polymerase and polyamine-oligonucleotide conjugate primer are also provided.
Public/Granted literature
- US20160281153A1 ISOTHERMAL AMPLIFICATION USING OLIGOCATION-CONJUGATED PRIMER SEQUENCES Public/Granted day:2016-09-29
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