Various embodiments of a point-of-care hygiene dispenser and an electronic hand hygiene event monitoring system are disclosed. One embodiment is directed to point-of-care dispenser and a corresponding electronic monitoring system, wherein the point-of-care dispenser is movable between predetermined zones of interest. Another embodiment is directed to a secure point-of-care dispenser having corresponding dispenser cover and main body interlocks. A still further embodiment is directed to point-of-care dispensing system comprising a point-of-care dispenser having a dispenser cover and a main body, a locking mechanism configured to secure the dispenser covers with the main body in a closed condition, and a docking unit configured for mounting with the point-of-care dispenser.