A minimal quantity lubrication grinding device including: heat pipe grinding wheel covered with electrocaloric film material on both side surfaces, wherein external electric field is applied to outside of the electrocaloric film material; and electrostatic atomization combined nozzle provided with high-voltage DC electrostatic generator and magnetic field forming device at the outside and in an electrocaloric refrigeration and magnetically enhanced electric field; electrostatic atomization combined nozzle is respectively connected with nanoparticle liquid and gas supply system; and nanofluid is electrostatically atomized by electrostatic atomization combined nozzle and is jet to grinding area to absorb heat of grinding area; electrocaloric film material absorbs heat in grinding area through electrocaloric effect and disperses absorbed heat through heat pipe grinding wheel after leaving grinding area to form a Carnot cycle. Nanofluid electrostatic atomization is integrated with electrocaloric refrigeration and heat pipe.