- 专利标题： Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication
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申请号： US15115758申请日： 2015-02-10
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公开(公告)号： US09932356B2公开(公告)日： 2018-04-03
- 发明人: John F. Kadow , David R. Langley , B. Narasimhulu Naidu , Kevin Peese , Zhongyu Wang
- 申请人： VIIV HEALTHCARE UK (No. 5) LIMITED
- 申请人地址： GB Brentford, Middlesex
- 专利权人： ViiV HEALTHCARE UK (NO. 5) LIMITED
- 当前专利权人： ViiV HEALTHCARE UK (NO. 5) LIMITED
- 当前专利权人地址： GB Brentford, Middlesex
- 代理商 Robert H. Brink; Edward R. Gimmi; William R. Majarian
- 国际申请： PCT/US2015/015154 WO 20150210
- 国际公布： WO2015/123182 WO 20150820
- 主分类号： C07D513/22
- IPC分类号： C07D513/22 ; C07D498/22 ; C07D471/22
摘要：
The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.