Invention Grant
- Patent Title: Endoglin polypeptides and uses thereof
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Application No.: US14112620Application Date: 2012-04-19
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Publication No.: US09932386B2Publication Date: 2018-04-03
- Inventor: Asya Grinberg , Roselyne Castonguay , Eric Werner , Ravindra Kumar
- Applicant: Asya Grinberg , Roselyne Castonguay , Eric Werner , Ravindra Kumar
- Applicant Address: US MA Cambridge
- Assignee: Acceleron Pharma, Inc.
- Current Assignee: Acceleron Pharma, Inc.
- Current Assignee Address: US MA Cambridge
- International Application: PCT/US2012/034295 WO 20120419
- International Announcement: WO2012/145539 WO 20121026
- Main IPC: C07K14/705
- IPC: C07K14/705 ; A61K38/00
Abstract:
In certain aspects, the present disclosure relates to the insight that a polypeptide comprising a truncated, ligand-binding portion of the extracellular domain of endoglin (ENG) polypeptide may be used to inhibit angiogenesis in vivo, particularly in mammals suffering angiogenesis-related disorders.
Public/Granted literature
- US20150307588A1 ENDOGLIN POLYPEPTIDES AND USES THEREOF Public/Granted day:2015-10-29
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