The present invention provides a signal sending method and a signal sending device, where the signal sending method includes: canceling interference from symbols of a boundary between at least two precoding code blocks in a multiple input multiple output filter bank multicarrier MIMO-FBMC system, where the precoding code block includes at least one time-frequency resource element that uses same precoding; performing precoding on a to-be-sent symbol in the precoding code block to obtain a precoded symbol; and sending the precoded symbol. In the present invention, mutual interference between precoding code blocks at a time-frequency critical location can be completely or partially canceled.