Invention Grant
- Patent Title: Isothiazolopyrimidinones, pyrazolopyrimidinones, and pyrrolopyrimidinones as ubiquitin-specific protease 7 inhibitors
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Application No.: US15015566Application Date: 2016-02-04
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Publication No.: US09938300B2Publication Date: 2018-04-10
- Inventor: Stephanos Ioannidis , Adam Charles Talbot , Bruce Follows , Alexandre Joseph Buckmelter , Minghua Wang , Ann-Marie Campbell
- Applicant: Forma Therapeutics, Inc.
- Applicant Address: US MA Watertown
- Assignee: Forma Therapeutics, Inc.
- Current Assignee: Forma Therapeutics, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Choate, Hall and Stewart LLP
- Agent John P. Rearick; Michael A. Shinall
- Main IPC: A01N43/90
- IPC: A01N43/90 ; A61K31/519 ; C07D471/00 ; C07D487/00 ; C07D513/04 ; C07D487/04
Abstract:
The disclosure relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula: where R1, R2, R3, R4, R5, R5′, X1, X2, X3, n, and m are described herein.
Public/Granted literature
Information query
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