The present subject matter discloses methods and systems of application sharing in multi-host computing system (100) running multiple operating systems. In one embodiment, the method for application sharing in a multi-host computing system (100) comprises receiving a request to launch an application in a first operating system of the multi-host computing system (100) from a second operating system of the multi-host computing system (100), generating an application launch request to launch the application and transmitting the application launch request to a widget daemon running on the first operating system using a PCIe to PCIe application redirection engine. The method further comprises initiating an application sharing session between the first operating system of the multi-host computing system (100) from the second operating system of the multi-host computing system (100).