- 专利标题： Standardized ex vivo platforms for the antigen-specific expansion of CD4+ T cell populations
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申请号： US14398496申请日： 2013-05-08
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公开(公告)号： US09943578B2公开(公告)日： 2018-04-17
- 发明人: Douglas Wayne Ethell
- 申请人： WESTERN UNIVERSITY OF HEALTH SCIENCES
- 申请人地址： US CA Pomona
- 专利权人： Western University of Health Sciences
- 当前专利权人： Western University of Health Sciences
- 当前专利权人地址： US CA Pomona
- 代理机构： Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- 国际申请： PCT/US2013/040172 WO 20130508
- 国际公布： WO2013/169922 WO 20131114
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; A61K39/00 ; A61K39/385 ; C12N5/0783 ; C12N5/0784
摘要：
The invention relates to methods, peptides, nucleic acids and cells for use in isolating and expanding human T cell populations in an antigen-specific manner for immunodiagnostic or therapeutic purposes. The invention also relates to professional antigen presenting cells derived from pluripotent human stem cells, and to customizable antigen presentation by the antigen presenting cells.
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