Invention Grant
- Patent Title: Factor XIa inhibitors
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Application No.: US15116547Application Date: 2015-02-06
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Publication No.: US09944643B2Publication Date: 2018-04-17
- Inventor: Santhosh F. Neelamkavil , Scott D. Edmondson , Alan W. Hruza , Zahid Hussain , Charles Lesburg , Remond Moningka
- Applicant: MERCK SHARP & DOHME CORP. , Santhosh F. Neelamkavil , Scott D. Edmondson , Alan W. Hruza , Zahid Hussain , Charles Lesburg , Remond Moningka
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Nicole M. Beeler; John C. Todaro
- International Application: PCT/US2015/014711 WO 20150206
- International Announcement: WO2015/123093 WO 20150820
- Main IPC: C07D471/08
- IPC: C07D471/08 ; C07D487/08
Abstract:
The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma kallikrein.
Public/Granted literature
- US20160376272A1 FACTOR XIa INHIBITORS Public/Granted day:2016-12-29
Information query
