Invention Grant
- Patent Title: Process for producing alkynylketone derivative
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Application No.: US15314181Application Date: 2015-05-28
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Publication No.: US09951051B2Publication Date: 2018-04-24
- Inventor: Genta Tadano , Fumiya Ikarashi , Kazuya Okamoto , Toshikatsu Maki , Motoyuki Hagihara
- Applicant: Shionogi & Co., Ltd.
- Applicant Address: JP Osaka
- Assignee: SHIONOGI & CO., LTD.
- Current Assignee: SHIONOGI & CO., LTD.
- Current Assignee Address: JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2014-111333 20140529
- International Application: PCT/JP2015/065336 WO 20150528
- International Announcement: WO2015/182682 WO 20151203
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D239/94 ; C07D295/03 ; C07C321/04 ; C07D413/12

Abstract:
The present invention relates to a Sonogashira-Carbonylation reaction using two types of gas, as well as novel crystals which can control a heat of the said reaction and the process of producing the same. In addition, the present invention relates to a ligand (additive) to prevent the deactivation of a palladium catalyst.
Public/Granted literature
- US20170197943A1 PROCESS FOR PRODUCING ALKYNYLKETONE DERIVATIVE Public/Granted day:2017-07-13
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