- 专利标题： Anti-C. difficile toxin antibodies and associated methods
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申请号： US14344749申请日： 2012-09-13
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公开(公告)号： US09957305B2公开(公告)日： 2018-05-01
- 发明人: Jimmy D. Ballard , Jordi M. Melton , Latisha Heinlen , Elaine E. Hamm
- 申请人： Jimmy D. Ballard , Jordi M. Melton , Latisha Heinlen , Elaine E. Hamm
- 申请人地址： US OK Norman
- 专利权人： The Board of Regents of the University of Oklahoma
- 当前专利权人： The Board of Regents of the University of Oklahoma
- 当前专利权人地址： US OK Norman
- 代理机构： Winstead PC
- 国际申请： PCT/US2012/055228 WO 20120913
- 国际公布： WO2013/040254 WO 20130321
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K14/33 ; A61K39/08 ; C07K16/12 ; G01N33/569
摘要：
Embodiments of the invention are directed to a composition comprising a recombinant protein in soluble form wherein said recombinant protein comprises a portion of the Clostridium difficile toxin B sequence that comprises an epitope for anti-toxin B antibody. Other embodiments of the invention are directed to the generation of antibodies using peptide fragments of C. difficile toxin B.
公开/授权文献
- US20150104454A1 ANTI-C.DIFFICILE TOXIN ANTIBODIES AND ASSOCIATED METHODS 公开/授权日：2015-04-16
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