The present invention provides an in-cell touch screen and a drive method thereof. The in-cell touch screen comprises a first substrate and a first electrode layer provided above the first substrate, wherein, the first electrode layer comprises touch control drive electrodes, touch control sensing electrodes and touch control amplification electrodes, which are mutually insulated, the touch control amplification electrodes are provided in a gap between the touch control drive electrodes and the touch control sensing electrodes, during a display phase, at least the touch control drive electrodes and the touch control sensing electrodes are applied with a common voltage, and during a touch control phase, the touch control drive electrodes are applied with a touch control drive signal, and the touch control sensing electrodes output touch control sensing signals.