Invention Grant
- Patent Title: 6-heteroaryloxy- or 6-aryloxy-quinoline-2-carboxamides and method of use
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Application No.: US15239554Application Date: 2016-08-17
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Publication No.: US09969693B2Publication Date: 2018-05-15
- Inventor: Andrew Bogdan , Marlon D. Cowart , David A. DeGoey , Tammie K. Jinkerson , John R. Koenig , Michael E. Kort , Bo Liu , Mark A. Matulenko , Derek W. Nelson , Meena V. Patel , Hillary Peltier , Marc J. Scanio , Brian D. Wakefield
- Applicant: AbbVie Inc.
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Main IPC: C07D215/48
- IPC: C07D215/48 ; C07D401/12 ; C07D409/14 ; C07D487/08 ; C07D401/14 ; C07D487/04 ; C07D405/14 ; C07D417/14 ; C07D471/04

Abstract:
Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein R1, R2, and R3 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by voltage-gated sodium channels, e.g., Nav 1.7 and/or Nav 1.8. Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
Public/Granted literature
- US20170226062A9 6-HETEROARYLOXY- OR 6-ARYLOXY-QUINOLINE-2-CARBOXAMIDES AND METHOD OF USE Public/Granted day:2017-08-10
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