发明授权
- 专利标题： IRE-1α inhibitors
-
申请号： US15356292申请日： 2016-11-18
-
公开(公告)号： US09981901B2公开(公告)日： 2018-05-29
- 发明人: John B. Patterson , David G. Lonergan , Gary A. Flynn , Qingping Zeng , Peter V. Pallai
- 申请人： FOSUN ORINOVE PHARMATECH, INC.
- 申请人地址： CN Suzhou
- 专利权人： FOSUN ORINOVE PHARMATECH, INC.
- 当前专利权人： FOSUN ORINOVE PHARMATECH, INC.
- 当前专利权人地址： CN Suzhou
- 代理机构： K&L Gates LLP
- 代理商 Louis C. Cullman; Benjamin Heuberger
- 主分类号： C07C235/42
- IPC分类号： C07C235/42 ; A61K31/166 ; C07C65/21 ; C07C65/26 ; C07C65/11 ; C07C233/65
摘要：
Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.
公开/授权文献
- US20170152206A1 IRE-1alpha INHIBITORS 公开/授权日：2017-06-01
信息查询
