An electronic device including a physical button, a processing unit and a sensing unit is provided. The processing unit is coupled to the physical button and the sensing unit is coupled to the processing unit. When the electronic device enters a hibernation mode or in a shutdown state, the sensing unit continuously detects a wake-up signal. When receiving the wake-up signal, the sensing unit wakes up the processing unit. The sensing unit further receives an instruction signal externally, generates an instruction information according to the instruction signal, and sends the instruction information to the processing unit. When receiving the instruction information, the processing unit adjusts a corresponding function of the physical button according to the instruction information.