- 专利标题: Detecting and visualizing correlations between measured correlation values and correlation reference values of a pathway
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申请号: US15178002申请日: 2016-06-09
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公开(公告)号: US09990713B2公开(公告)日: 2018-06-05
- 发明人: Ralf Schoenmeyer , Sonja Althammer , Guenter Schmidt
- 申请人: Definiens AG
- 申请人地址: DE Munich
- 专利权人: Definiens AG
- 当前专利权人: Definiens AG
- 当前专利权人地址: DE Munich
- 代理机构: Imperium Patent Works
- 代理商 Darien K. Wallace
- 主分类号: G06T7/00
- IPC分类号: G06T7/00 ; G06F19/10 ; G06F19/00 ; G06K9/00
摘要:
An analysis and visualization system analyzes a digital image of a tissue sample. In the sample, cells of a first type are stained in a first way, and cells of a second type are stained in a second way. The system segments the high-resolution image into first and second objects representing cells of the first and second types, respectively. The system also identifies a region of interest, and divides it into tiles. The system generates, for each tile, a first value and a second value. The first and second values for a tile are indicative of densities of the first and second objects in the tile. From the values, a measured correlation coefficient (CC) value is determined. The system compares the measured CC value to a reference CC value, thereby obtaining a correspondence value. The system then displays the image region along with a visualization of the correspondence value.
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