- 专利标题： Preparation and use of a composition for prevention and mitigation of the effects of radiation
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申请号： US15021376申请日： 2014-09-15
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公开(公告)号： US09993456B2公开(公告)日： 2018-06-12
- 发明人: Cesar M. Compadre , Philip Breen , Nukhet Aykin-Burns , Martin Hauer-Jensen , Raul G. Enriquez , Sujay Kharade , Omar Malagon , Yadira Ordonez , Edgar Ojeda , Shraddha Thakkar , E. Nathalie Pineda , Darin Jones
- 申请人： BioVentures, LLC , Universidad Tecnica Particular De Loja , The United States of America as Represented by the Department of Veterans Affairs
- 申请人地址： US AR Little Rock EC Loja US DC Washington
- 专利权人： The Board of Trustees of the University of Arkansas,Universidad Tecnica Particular De Loja,The United States of America as Represented by the Department of Veterans Affairs
- 当前专利权人： The Board of Trustees of the University of Arkansas,Universidad Tecnica Particular De Loja,The United States of America as Represented by the Department of Veterans Affairs
- 当前专利权人地址： US AR Little Rock EC Loja US DC Washington
- 代理机构： Andrus Intellectual Property Law, LLP
- 国际申请： PCT/US2014/055657 WO 20140915
- 国际公布： WO2015/039029 WO 20150319
- 主分类号： A61K31/35
- IPC分类号： A61K31/35 ; A61K31/355 ; A61K36/185
摘要：
Plant extracts, compositions, pharmaceutical compositions and methods of making and using the same are provided herein. The compositions comprise γ-tocotrienol (GT3) and δ-tocotrienol (DT3) in ratios wherein the DT3 is predominate. The compositions are useful for radioprotection and radiomitigation in subjects in need thereof.
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