发明授权
- 专利标题： Combination Alzheimer therapy using anti-N3pGlu Abeta antibodies + a BACE inhibitor
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申请号： US15503027申请日： 2015-09-08
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公开(公告)号： US09999624B2公开(公告)日： 2018-06-19
- 发明人: Patrick Cornelious May , Dustin James Mergott
- 申请人： Eli Lilly and Company
- 申请人地址： US IN Indianapolis
- 专利权人： Eli Lilly and Company
- 当前专利权人： Eli Lilly and Company
- 当前专利权人地址： US IN Indianapolis
- 代理商 Nelsen L. Lentz
- 国际申请： PCT/US2015/048807 WO 20150908
- 国际公布： WO2016/043997 WO 20160324
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K31/542 ; C07K16/18 ; C07D513/04 ; A61K45/06 ; A61K39/00
摘要：
The present invention provides a method of treating a cognitive or neurodegenerative disease, comprising administering to a patient in need of such treatment an effective amount of a compound of the formula I, or a pharmaceutically acceptable salt thereof; in combination with an effective amount of an anti-N3pGlu Abeta monoclonal antibody.
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