- 专利标题： Selective agents for pain suppression
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申请号： US15267953申请日： 2016-09-16
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公开(公告)号： USRE47475E1公开(公告)日： 2019-07-02
- 发明人: James M. Cook , Shengming Huang , Rahul Edwankar , Ojas A. Namjoshi , Zhi-Jian Wang , Qi Huang , Xiaohui He , Xiaoyan Li , Jianming Yu , Dongmei Han
- 申请人： WiSys Technology Foundation, Inc.
- 申请人地址： US WI Madison
- 专利权人： WISYS TECHNOLOGY FOUNDATION, INC.
- 当前专利权人： WISYS TECHNOLOGY FOUNDATION, INC.
- 当前专利权人地址： US WI Madison
- 代理机构： Boyle Fredrickson S.C.
- 主分类号： A61K31/5517
- IPC分类号： A61K31/5517 ; C07D487/02 ; C07D243/12 ; C07D519/00 ; C07D471/04 ; C07D487/06 ; C07D487/04 ; C07D243/20 ; C07D495/04 ; C07D243/24 ; C07D498/04
摘要：
In preferred embodiments, the present invention provides methods of treatment and pharmaceutical compositions for the suppression, alleviation and prevention of the often chronic, severe and debilitating pain that can accompany inflammatory diseases and neuropathic insults, pain that is often unresponsive to conventional analgesic treatment. The preferred embodiments of the present invention further relate to methods of treatment and pharmaceutical compositions using benzodiazepine derivatives that provide suppression, alleviation and prevention of neuropathic pain, migraine-related pain and inflammatory pain with reduced sedative and ataxic side effects.
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