发明申请
- 专利标题: THERAPEUTIC INHIBITOR OF VASCULAR SMOOTH MUSCLE CELLS
- 专利标题(中): 血管平滑肌细胞的治疗抑制剂
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申请号: PCT/US1992008220申请日: 1992-09-25
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公开(公告)号: WO1994007529A1公开(公告)日: 1994-04-14
- 发明人: NEORX CORPORATION
- 申请人: NEORX CORPORATION , KUNZ, Lawrence, Leroy
- 专利权人: NEORX CORPORATION,KUNZ, Lawrence, Leroy
- 当前专利权人: NEORX CORPORATION,KUNZ, Lawrence, Leroy
- 主分类号: A61K39/00
- IPC分类号: A61K39/00
摘要:
Methods are provided for inhibiting stenosis following vascular trauma or disease in a mammalian host, comprising administering to the host a therapeutically effective dosage of a therapeutic conjugate containing a vascular smooth muscle binding protein that associates in a specific manner with a cell surface of the vascular smooth muscle cell, coupled to a therapeutic agent that inhibits a cellular activity of the muscle cell.