Invention Application
WO9934833A9 DEGRADABLE HETEROBIFUNCTIONAL POLY(ETHYLENE GLYCOL) ACRYLATES AND GELS AND CONJUGATES DERIVED THEREFROM
审中-公开
可降解的异戊二烯（乙二醇）丙烯酸酯和凝胶以及其衍生物
- Patent Title: DEGRADABLE HETEROBIFUNCTIONAL POLY(ETHYLENE GLYCOL) ACRYLATES AND GELS AND CONJUGATES DERIVED THEREFROM
- Patent Title (中): 可降解的异戊二烯（乙二醇）丙烯酸酯和凝胶以及其衍生物
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Application No.: PCT/US9900594Application Date: 1999-01-06
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Publication No.: WO9934833A9Publication Date: 2005-03-17
- Inventor: HARRIS J MILTON , ZHAO XUAN
- Applicant: SHEARWATER POLYMERS INC , HARRIS J MILTON , ZHAO XUAN
- Assignee: SHEARWATER POLYMERS INC,HARRIS J MILTON,ZHAO XUAN
- Current Assignee: SHEARWATER POLYMERS INC,HARRIS J MILTON,ZHAO XUAN
- Priority: US7068098 1998-01-07
- Main IPC: A61K47/48
- IPC: A61K47/48 ; C08F299/00 ; C08G65/329 ; C08G81/00
Abstract:
A heterobifunctional poly(ethylene glycol) is provided having a hydrolytically degradable linkage, a first terminus comprising an acrylate group, and a second terminus comprising a target such as a protein or pharmaceutical agent or a reactive moiety capable of coupling to a target. Hydrogels can be prepared. The hydrogels can be used as a carrier for a protein or a pharmaceutical agent that can be readily released in a controlled fashion.
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