Invention Application
WO01014390A3 METABOTROPIC GLUTAMATE RECEPTOR LIGAND DERIVATIVES AS NAALADase INHIBITORS
审中-公开
代谢谷氨酸受体配体衍生物作为NAALADase抑制剂
- Patent Title: METABOTROPIC GLUTAMATE RECEPTOR LIGAND DERIVATIVES AS NAALADase INHIBITORS
- Patent Title (中): 代谢谷氨酸受体配体衍生物作为NAALADase抑制剂
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Application No.: PCT/US2000/022412Application Date: 2000-08-16
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Publication No.: WO01014390A3Publication Date: 2001-09-27
- Main IPC: C07C229/14
- IPC: C07C229/14 ; C07C229/16 ; C07C229/46 ; C07C259/08 ; C07F9/30 ; C07F9/38 ; C07F9/572 ; C07F9/6561 ; C07F9/44 ; C07C229/50 ; C07F9/40
Abstract:
The present invention relates to metabotropic glutamate receptor ligand derivatives and methods of using the same to inhibit NAALADase enzyme activity, to effect neuronal activities, to inhibit angiogenesis, and to treat glutamate abnormalities, compulsive disorders, pain, diabetic neuropathy, and prostate diseases, as well as pharmaceutical compositions comprising the same.
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