发明申请
WO02016327A1 BENZIMIDAZOLES AND ANALOGUES AND THEIR USE AS NEUTROPHIL INHIBITORS
审中-公开
苯并咪唑和类似物及其作为中性抑制剂的用途
- 专利标题: BENZIMIDAZOLES AND ANALOGUES AND THEIR USE AS NEUTROPHIL INHIBITORS
- 专利标题(中): 苯并咪唑和类似物及其作为中性抑制剂的用途
-
申请号: PCT/US2001/025224申请日: 2001-08-10
-
公开(公告)号: WO02016327A1公开(公告)日: 2002-02-28
- 主分类号: A61P29/00
- IPC分类号: A61P29/00 ; C07D235/06 ; C07D235/08 ; C07D235/26 ; C07D235/30 ; C07D241/42 ; C07D263/58 ; C07D277/62 ; C07D403/12 ; C07D409/12 ; C07D413/12 ; C07F9/6506 ; A61K31/4184 ; A61K31/423 ; A61K31/428 ; A61K31/498 ; A61K31/675 ; C07C235/30
摘要:
The invention provides novel compounds selected from the group consisting of formula (I) and (II). The compounds of the present invention are useful for the treatment and prevention of a variety of diseases and conditions associated with undesirable or abnormal inflammatory responses, such as ischemia-reperfusion injury. Accordingly, the invention further provides pharmaceutical compositions comprising these compounds. The invention still further provides methods of treatment or prevention for the above disorders using theses compounds or the compositions containing them.