Invention Application
- Patent Title: INHIBITORS OF INTEGRIN αvβ6
- Patent Title (中): INTEGRIN alpha v beta 6的抑制剂
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Application No.: PCT/EP2002/001836Application Date: 2002-02-21
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Publication No.: WO2002074730A1Publication Date: 2002-09-26
- Inventor: SCHADT, Oliver , JONCZYK, Alfred , STÄHLE, Wolfgang , GOODMAN, Simon
- Applicant: MERCK PATENT GMBH , SCHADT, Oliver , JONCZYK, Alfred , STÄHLE, Wolfgang , GOODMAN, Simon
- Applicant Address: Frankfurter Strasse 250, 64293 Darmstadt DE
- Assignee: MERCK PATENT GMBH,SCHADT, Oliver,JONCZYK, Alfred,STÄHLE, Wolfgang,GOODMAN, Simon
- Current Assignee: MERCK PATENT GMBH,SCHADT, Oliver,JONCZYK, Alfred,STÄHLE, Wolfgang,GOODMAN, Simon
- Current Assignee Address: Frankfurter Strasse 250, 64293 Darmstadt DE
- Agency: MERCK PATENT GMBH
- Priority: DE101 20010316
- Main IPC: C07C237/04
- IPC: C07C237/04
Abstract:
Novel biphenyl derivatives of the general formula (I) in which R 1 , R 1' , R 1" , R 2 , R 2' , R 3 and n are as defined in Claim 1, their stereoisomers and their physiologically acceptable salts or solvates are novel integrin inhibitors which preferentially inhibit the α v β 6 integrin receptor. The novel compounds can be used, in particular, as medicaments.
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