Invention Application
WO2003066808A2 MAMMALIAN MIGRATION INDUCTING GENE AND METHODS FOR DETECTION AND INHIBITION OF MIGRATING TUMOR CELLS
审中-公开
MAMMALIAN移植诱导基因和检测和抑制移植肿瘤细胞的方法
- Patent Title: MAMMALIAN MIGRATION INDUCTING GENE AND METHODS FOR DETECTION AND INHIBITION OF MIGRATING TUMOR CELLS
- Patent Title (中): MAMMALIAN移植诱导基因和检测和抑制移植肿瘤细胞的方法
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Application No.: PCT/US2003/002047Application Date: 2003-01-23
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Publication No.: WO2003066808A2Publication Date: 2003-08-14
- Inventor: LINDSEY, Suzanne, J.
- Applicant: TEXAS TECH UNIVERSITY , LINDSEY, Suzanne, J.
- Applicant Address: Technology Transfer And Intellectual Property, P.o. Box 42007, Lubbock, Tx Texas 79409-2007 US
- Assignee: TEXAS TECH UNIVERSITY,LINDSEY, Suzanne, J.
- Current Assignee: TEXAS TECH UNIVERSITY,LINDSEY, Suzanne, J.
- Current Assignee Address: Technology Transfer And Intellectual Property, P.o. Box 42007, Lubbock, Tx Texas 79409-2007 US
- Agency: GOLDMAN, Michael, L.
- Priority: US60/351,073 20020123
- Main IPC: C12N
- IPC: C12N
Abstract:
The present invention relates to isolated nucleic acid molecules conferring on mammalian carcinoma cells an ability to undergo cell migration. Recombinant DNA expression systems and host cells containing the subject nucleic acid molecule, as well as antisense oligonucleotides, are also described. Also disclosed are methods of inhibiting expresssion of the subject nucleic acid molecule, inhibiting production of the encoded protein or polypeptide, inhibiting metastasis of a carcinoma cell in a subject (including in humans), inhibiting migration of carcinoma cell in a subject, detecting the presence of a migrating carcinoma cell in a sample of a subject's tissue or body fluids, and inhibiting the migration of a placental cell into the blood stream of a female mammal.
Public/Granted literature
- WO2003066808A3 MAMMALIAN MIGRATION INDUCTING GENE AND METHODS FOR DETECTION AND INHIBITION OF MIGRATING TUMOR CELLS Public/Granted day:2003-08-14
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