An apparatus useable for circulatory isolation and treatment of a part of a patient's body comprising:- a fluid circulation loop having a first (132) and a second end (140);- obstructing means capable of obstructing a blood flow in a patient's blood vessel such that a body part or organ becomes circulatorily isolated from the circulation of the rest of the body;- flow-through means comprising a first and a second flow-through member connectable to said first (132) and second (140) end of said fluid circulation loop, respectively, for providing said part of the patient's body with a fluid connection to the fluid circulation loop, making it possible to circulate a therapeutic fluid through said body part.