发明申请
WO2003097581A1 CONTINUOUS PROCESS FOR THE CYANATION OF HYDROGENATED BETA-KETOESTERS
审中-公开
氢化β-酮醇酯的连续反应过程
- 专利标题: CONTINUOUS PROCESS FOR THE CYANATION OF HYDROGENATED BETA-KETOESTERS
- 专利标题(中): 氢化β-酮醇酯的连续反应过程
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申请号: PCT/GB2003/002173申请日: 2003-05-21
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公开(公告)号: WO2003097581A1公开(公告)日: 2003-11-27
- 发明人: PROCTOR, Lee, David , WARR, Antony, John
- 申请人: PHOENIX CHEMICALS LIMITED , PROCTOR, Lee, David , WARR, Antony, John
- 申请人地址: 34 Thursby Road, Croft Business Park, Bromborough, Wirral CH62 3PW GB
- 专利权人: PHOENIX CHEMICALS LIMITED,PROCTOR, Lee, David,WARR, Antony, John
- 当前专利权人: PHOENIX CHEMICALS LIMITED,PROCTOR, Lee, David,WARR, Antony, John
- 当前专利权人地址: 34 Thursby Road, Croft Business Park, Bromborough, Wirral CH62 3PW GB
- 代理机构: W.P. THOMPSON & CO.
- 优先权: GB0211715.8 20020522
- 主分类号: C07C253/14
- IPC分类号: C07C253/14
摘要:
The present invention relates to a continuous process for the cyanation of hydrogenated β-ketoesters in a cyanation zone maintained under conditions of temperature and pressure effective for cyanation of a hydrogenated R-ketoester. A substrate comprising a hydrogenated β-ketoester is continuously supplyed to the cyanation zone together with a cyanide. The substrate is contacted with the cyanide in the cyanation zone for a period effective for at least partial cyanation of the hydrogenated β-ketoester and a product stream is continuously extracted from the cyanation zone.