- 专利标题: CANCER-LINKED GENE AS TARGET FOR CHEMOTHERAPY
-
申请号: PCT/US2003/018400申请日: 2003-06-11
-
公开(公告)号: WO2003105758A2公开(公告)日: 2003-12-24
- 发明人: STROVEL, Jeffrey, William , EBNER, Reinhard
- 申请人: AVALON PHARMACEUTICALS, INC. , STROVEL, Jeffrey, William , EBNER, Reinhard
- 申请人地址: 20358 Seneca Meadows Parkway, Germantown, MD 20876 US
- 专利权人: AVALON PHARMACEUTICALS, INC.,STROVEL, Jeffrey, William,EBNER, Reinhard
- 当前专利权人: AVALON PHARMACEUTICALS, INC.,STROVEL, Jeffrey, William,EBNER, Reinhard
- 当前专利权人地址: 20358 Seneca Meadows Parkway, Germantown, MD 20876 US
- 代理机构: GRANT, Alan, J.
- 优先权: US60/388,157 20020612
- 主分类号: A61K
- IPC分类号: A61K
摘要:
Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with processes for assaying potential antitumor agents based on their modulation of the expression of these cancer-linked genes. Also disclosed are antibodies that react with the disclosed polypeptides and methods of using the antibodies to treat cancerous conditions, such as by using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agents thereto. Also described are methods of diagnosing using the gene sequences.
公开/授权文献
- WO2003105758A3 CANCER-LINKED GENE AS TARGET FOR CHEMOTHERAPY 公开/授权日:2003-12-24