Invention Application
- Patent Title: MODULATION OF NOTCH2 EXPRESSION
- Patent Title (中): NOTCH2表达式的调制
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Application No.: PCT/US2003/037405Application Date: 2003-11-21
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Publication No.: WO2004047750A2Publication Date: 2004-06-10
- Inventor: FREIER, Susan, M. , DOBIE, Kenneth, W.
- Applicant: ISIS PHARMACEUTICALS. INC. , FREIER, Susan, M. , DOBIE, Kenneth, W.
- Applicant Address: 2292 Faraday Avenue, Carlsbad, CA 92008 US
- Assignee: ISIS PHARMACEUTICALS. INC.,FREIER, Susan, M.,DOBIE, Kenneth, W.
- Current Assignee: ISIS PHARMACEUTICALS. INC.,FREIER, Susan, M.,DOBIE, Kenneth, W.
- Current Assignee Address: 2292 Faraday Avenue, Carlsbad, CA 92008 US
- Agency: LEGAARD, Paul, K.
- Priority: US10/303,165 20021122
- Main IPC: A61K
- IPC: A61K
Abstract:
Compounds, compositions and methods are provided for modulating the expression of Notch2. The compositions comprise oligonucleotides, targeted to nucleic acid encoding Notch2. Methods of using these compounds for modulation of Notch2 expression and for diagnosis and treatment of disease associated with expression of Notch2 are provided.
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