A multi-use sanitization system is disclosed which includes one or more containers in fluid communication with other system components. Components of the system include a vortex-venturi for incorporating ozone into a liquid, an ozone generator to provide ozone to the vortex-venturi, a double check valve to allow simultaneous flow of liquid into and out of the container, and a pump to promote fluid flow through the system. Optionally, a gas-liquid separator with an optional integral gas release valve, an ozone destructor, an oxidation-reduction potential ozone sensor, or a pour-through type pre-filter may be incorporated into the system.