发明申请
- 专利标题： CONJUGATION REACTIONS
- 专利标题（中）： 联合反应
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申请号： PCT/GB2004/000140申请日： 2004-01-16
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公开(公告)号： WO2004063237A1公开(公告)日： 2004-07-29
- 发明人: LEWIS, Andrew, Lennard , LEPPARD, Simon, William
- 申请人： BIOCOMPATIBLES UK LIMITED , LEWIS, Andrew, Lennard , LEPPARD, Simon, William
- 申请人地址： Chapman House, Farnham Business Park, Weydon Lane, Farnham, Surrey GU9 8QL GB
- 专利权人： BIOCOMPATIBLES UK LIMITED,LEWIS, Andrew, Lennard,LEPPARD, Simon, William
- 当前专利权人： BIOCOMPATIBLES UK LIMITED,LEWIS, Andrew, Lennard,LEPPARD, Simon, William
- 当前专利权人地址： Chapman House, Farnham Business Park, Weydon Lane, Farnham, Surrey GU9 8QL GB
- 代理机构： GILL JENNINGS & EVERY
- 优先权： GB0301014.7 20030116
- 主分类号： C08F246/00
- IPC分类号： C08F246/00
摘要：
An initiator for the terminal group of the polymer product of an atom or group radical transfer polymerisation has an activated carboxyl or an amine group which is reacted with an amine or carboxyl (respectively) group containing biologically active compound. The initiator is preferably 4-(3-(2 bromo, 2-methyl-prop ionate)phenyl)-prop ionic acid N-hydroxysuccinimide ester or 2-bromo, 2-methyl-propionic acid N-hydroxysuccinimide ester. The monomers preferably comprise a zwitterionic monomer such as 2- methacryloxyethyl-2'-trimethyl ammoniumethyl phosphate inner salt
