Invention Application
- Patent Title: NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS
- Patent Title (中): 非核苷酸逆转录酶抑制剂
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Application No.: PCT/EP2004/001477Application Date: 2004-02-17
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Publication No.: WO2004074257A1Publication Date: 2004-09-02
- Inventor: DUNN, James, Patrick , HOGG, Joan, Heather , MIRZADEGAN, Taraneh , SWALLOW, Steven
- Applicant: F. HOFFMANN-LA ROCHE AG , DUNN, James, Patrick , HOGG, Joan, Heather , MIRZADEGAN, Taraneh , SWALLOW, Steven
- Applicant Address: Grenzacherstrasse 124, CH-4070 Basel CH
- Assignee: F. HOFFMANN-LA ROCHE AG,DUNN, James, Patrick,HOGG, Joan, Heather,MIRZADEGAN, Taraneh,SWALLOW, Steven
- Current Assignee: F. HOFFMANN-LA ROCHE AG,DUNN, James, Patrick,HOGG, Joan, Heather,MIRZADEGAN, Taraneh,SWALLOW, Steven
- Current Assignee Address: Grenzacherstrasse 124, CH-4070 Basel CH
- Agency: SCHAGER, Frank
- Priority: US60/447,974 20030218
- Main IPC: C07D231/20
- IPC: C07D231/20
Abstract:
This invention relates to novel pyrazole derivatives of formula (I) wherein R1 to R4 are as defined in the summary and pharmaceutically acceptable salts and solvates thereof, methods to inhibits or modulate Human Immunodeficiency Virus (HIV) reverse transcriptase with compounds of formula (I) and pharmaceutical compositions of formula (I) admixed with at least one solvent, carrier or excipient. The compounds are useful for treating disorders in which HIV and genetically related viruses are implicated (formula I).
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