发明申请
- 专利标题： BENZAZEPINE DERIVATIVES AS MAO-B INHIBITORS
- 专利标题（中）： 苯并噻吩衍生物作为MAO-B抑制剂
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申请号： PCT/EP2004/011541申请日： 2004-10-14
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公开(公告)号： WO2005039591A1公开(公告)日： 2005-05-06
- 发明人: JOLIDON, Synese , RODRIGUEZ SARMIENTO, Rosa Maria , THOMAS, Andrew, William , WOSTL, Wolfgang , WYLER, Rene
- 申请人： F. HOFFMANN-LA ROCHE AG , JOLIDON, Synese , RODRIGUEZ SARMIENTO, Rosa Maria , THOMAS, Andrew, William , WOSTL, Wolfgang , WYLER, Rene
- 申请人地址： Grenzacherstrasse 124, CH-4070 Basel CH
- 专利权人： F. HOFFMANN-LA ROCHE AG,JOLIDON, Synese,RODRIGUEZ SARMIENTO, Rosa Maria,THOMAS, Andrew, William,WOSTL, Wolfgang,WYLER, Rene
- 当前专利权人： F. HOFFMANN-LA ROCHE AG,JOLIDON, Synese,RODRIGUEZ SARMIENTO, Rosa Maria,THOMAS, Andrew, William,WOSTL, Wolfgang,WYLER, Rene
- 当前专利权人地址： Grenzacherstrasse 124, CH-4070 Basel CH
- 代理机构： BRAUN, Axel
- 优先权： EP03024297.8 20031023
- 主分类号： A61K31/55
- IPC分类号： A61K31/55
摘要：
The present invention relates to novel benzazepine derivatives of the following formula: (I) wherein R 1 , R 2 , R 3 , R 4 and R 5 , X, X’, Y and Y’ are as defined in the description and claims, processes for their preparation, pharmaceutical compositions containing said derivatives and their use for the preparation of medicaments useful for the prevention and treatment of diseases in which selective inhibition of monoamine oxidase B activity plays a role or is implicated.
