Invention Application
WO2005049018A1 THIAZOLES AND OXAZOLES USEFUL AS MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS
审中-公开
作为ATP-结合CASSETTE TRANSPORTERS的调节剂的THIAZOLES和OXAZOLES有用
- Patent Title: THIAZOLES AND OXAZOLES USEFUL AS MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS
- Patent Title (中): 作为ATP-结合CASSETTE TRANSPORTERS的调节剂的THIAZOLES和OXAZOLES有用
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Application No.: PCT/US2004/038566Application Date: 2004-11-15
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Publication No.: WO2005049018A1Publication Date: 2005-06-02
- Inventor: HADIDA RUAH, Sarah, S , MILLER, Mark, T. , GROOTENHUIS, Peter, D., J. , HAMILTON, Matthew?
- Applicant: VERTEX PHARMACEUTICALS INCORPORATED , HADIDA RUAH, Sarah, S , MILLER, Mark, T. , GROOTENHUIS, Peter, D., J. , HAMILTON, Matthew?
- Applicant Address: 130 Waverly Street, Cambridge, MA 02139 US
- Assignee: VERTEX PHARMACEUTICALS INCORPORATED,HADIDA RUAH, Sarah, S,MILLER, Mark, T.,GROOTENHUIS, Peter, D., J.,HAMILTON, Matthew?
- Current Assignee: VERTEX PHARMACEUTICALS INCORPORATED,HADIDA RUAH, Sarah, S,MILLER, Mark, T.,GROOTENHUIS, Peter, D., J.,HAMILTON, Matthew?
- Current Assignee Address: 130 Waverly Street, Cambridge, MA 02139 US
- Agency: GOVINDASWAMY, Nandakumar
- Priority: US60/520,355 20031114
- Main IPC: A61K31/42
- IPC: A61K31/42
Abstract:
The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
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