Invention Application
WO2005086706A2 MULTI-PHASED, BIODEGRADABLE AND OSTEOINTEGRATIVE COMPOSITE SCAFFOLD FOR BIOLOGICAL FIXATION OF MUSCULOSKELETAL SOFT TISSUE TO BONE
审中-公开
用于骨骼肌细胞软骨组织生物固定的多阶段生物可降解和OSTEOINTEGRATIVE COMPOSITE SCAFFOLD
- Patent Title: MULTI-PHASED, BIODEGRADABLE AND OSTEOINTEGRATIVE COMPOSITE SCAFFOLD FOR BIOLOGICAL FIXATION OF MUSCULOSKELETAL SOFT TISSUE TO BONE
- Patent Title (中): 用于骨骼肌细胞软骨组织生物固定的多阶段生物可降解和OSTEOINTEGRATIVE COMPOSITE SCAFFOLD
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Application No.: PCT/US2005/007129Application Date: 2005-03-04
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Publication No.: WO2005086706A2Publication Date: 2005-09-22
- Inventor: LU, Helen, H. , SPALAZZI, Jeffrey , DIONISIO, Kathie
- Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK , LU, Helen, H. , SPALAZZI, Jeffrey , DIONISIO, Kathie
- Applicant Address: West 116th Street and Broadway, New York, NY 10027 US
- Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK,LU, Helen, H.,SPALAZZI, Jeffrey,DIONISIO, Kathie
- Current Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK,LU, Helen, H.,SPALAZZI, Jeffrey,DIONISIO, Kathie
- Current Assignee Address: West 116th Street and Broadway, New York, NY 10027 US
- Agency: WHITE, John, P.
- Priority: US60/550,700 20040305
- Main IPC: A61F2/00
- IPC: A61F2/00 ; A61F2/02 ; A61F2/08 ; A61F2/30 ; A61L27/38 ; A61L27/44 ; A61L27/46
Abstract:
Methods and apparatuses are provided for musculoskeletal tissue engineering. For example, a scaffold apparatus is provided which comprises microspheres of selected sizes and/or composition. The microspheres are layered to have a gradient of microsphere sizes and/or compositions. The scaffold provides a functional interface between multiple tissue types.
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