发明申请
WO2005087715A1 METHOD FOR THE PREPARATION OF 3-SUBSTITUTED-3’-HYDROXYPROPIONITRILE
审中-公开
制备3-取代-3'-羟基丙酸酯的方法
- 专利标题： METHOD FOR THE PREPARATION OF 3-SUBSTITUTED-3’-HYDROXYPROPIONITRILE
- 专利标题（中）： 制备3-取代-3'-羟基丙酸酯的方法
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申请号： PCT/KR2004/000531申请日： 2004-03-13
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公开(公告)号： WO2005087715A1公开(公告)日： 2005-09-22
- 发明人: SONG, Jeong-Ho , YUN, Jin-Won , LEE, Ho-Seong , KIM, Ho-Cheol , KIM, Seong-Jin
- 申请人： RSTECH CORPORATION , SONG, Jeong-Ho , YUN, Jin-Won , LEE, Ho-Seong , KIM, Ho-Cheol , KIM, Seong-Jin
- 申请人地址： #306 Venture Town Jangyoungsilgwan, 1688-5, Sinil-dong, Daeduk-gu, Daejeon 306-230 KR
- 专利权人： RSTECH CORPORATION,SONG, Jeong-Ho,YUN, Jin-Won,LEE, Ho-Seong,KIM, Ho-Cheol,KIM, Seong-Jin
- 当前专利权人： RSTECH CORPORATION,SONG, Jeong-Ho,YUN, Jin-Won,LEE, Ho-Seong,KIM, Ho-Cheol,KIM, Seong-Jin
- 当前专利权人地址： #306 Venture Town Jangyoungsilgwan, 1688-5, Sinil-dong, Daeduk-gu, Daejeon 306-230 KR
- 代理机构： KIM, Jin-Hak
- 主分类号： C07C255/12
- IPC分类号： C07C255/12
摘要：
The present invention relates to a method for the preparation of 3-substituted-3’-hydroxypropionitrile, more particularly, to a method for the preparation of 3-substituted-3’-hydroxypropionitrile which comprises performing ring opening of 1-substituted-ethylene oxide using sodium cyanide and citric acid in a range of pH 7.8 ~ 8.3 to provide 3-substituted-3’-hydroxypropionitrile in high optical purity and with high yield.
