Invention Application
- Patent Title: APPARATUS AND METHOD FOR CELL MIGRATION ASSAYS
- Patent Title (中): 细胞迁移测定的装置和方法
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Application No.: PCT/US2005/034627Application Date: 2005-09-28
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Publication No.: WO2006047038A1Publication Date: 2006-05-04
- Inventor: WALT, David, R. , DI CESARE, Christopher, J.
- Applicant: TRUSTEES OF TUFTS COLLEGE , WALT, David, R. , DI CESARE, Christopher, J.
- Applicant Address: 75 Kneeland Street, Boston, MA 02111 US
- Assignee: TRUSTEES OF TUFTS COLLEGE,WALT, David, R.,DI CESARE, Christopher, J.
- Current Assignee: TRUSTEES OF TUFTS COLLEGE,WALT, David, R.,DI CESARE, Christopher, J.
- Current Assignee Address: 75 Kneeland Street, Boston, MA 02111 US
- Agency: SILVA, Robin, M. et al.
- Priority: US60/614,196 20040928
- Main IPC: C12M1/34
- IPC: C12M1/34 ; G01N21/64 ; G01N33/543
Abstract:
The present invention is directed to a method and apparatus for detecting and analyzing cell migration. More specifically, the present invention is directed to novel technology for analyzing cellular movement, including whole cell migration and subcellular component movement. Cells are distributed onto a substrate and monitored for migration or movement. According to one embodiment, when a labelled cell or portion of a cell passes over one of the delineations between detection units, such as individual fibers in a fiber optic bundle, the label causes a large intensity increase, which stays for a given "residence time" until the cell departs from the detection unit. Each cell is disposed over at least one detection unit.
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