发明申请
- 专利标题: TUBULIN BINDING ANTI CANCER AGENTS AND PRODRUGS THEREOF
- 专利标题(中): TUBULIN BINDING抗癌剂及其制剂
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申请号: PCT/US2005042095申请日: 2005-11-17
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公开(公告)号: WO2006057946A3公开(公告)日: 2007-07-05
- 发明人: MATTEUCCI MARK , DUAN JIAN-XIN , CAI XIAOHONG
- 申请人: THRESHOLD PHARMACEUTICALS INC , MATTEUCCI MARK , DUAN JIAN-XIN , CAI XIAOHONG
- 专利权人: THRESHOLD PHARMACEUTICALS INC,MATTEUCCI MARK,DUAN JIAN-XIN,CAI XIAOHONG
- 当前专利权人: THRESHOLD PHARMACEUTICALS INC,MATTEUCCI MARK,DUAN JIAN-XIN,CAI XIAOHONG
- 优先权: US63042204 2004-11-22; US72692805 2005-10-14
- 主分类号: C07D235/00
- IPC分类号: C07D235/00 ; A01N43/42 ; A61K31/44 ; A61K31/50 ; C07D221/02 ; C07D231/54 ; C07D253/02 ; C07D471/02 ; C07D487/00 ; C07D491/02 ; C07D498/02
摘要:
Novel tubulin binding compounds and hypoxia activated prodrugs of novel and known tubulin binding compounds useful for treating cancer and other hyperproliferative diseases are disclosed.