Invention Application
- Patent Title: NOVEL LACTAME DERIVATIVES AS RENIN INHIBITORS
- Patent Title (中): 新颖的Lactals衍生物作为RININ抑制剂
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Application No.: PCT/IB2005054008Application Date: 2005-12-01
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Publication No.: WO2006059304A3Publication Date: 2006-10-12
- Inventor: BEZENCON OLIVIER , BOSS CHRISTOPH , BUR DANIEL , CORMINBOEUF OLIVIER , FISCHLI WALTER , GRISOSTOMI CORINNA , REMEN LUBOS , RICHARD-BILDSTEIN SYLVIA , SIFFERLEN THIERRY , WELLER THOMAS , MACDONALD DWIGHT , MCKAY DANIEL , POWELL DAVID A
- Applicant: ACTELION PHARMACEUTICALS LTD , BEZENCON OLIVIER , BOSS CHRISTOPH , BUR DANIEL , CORMINBOEUF OLIVIER , FISCHLI WALTER , GRISOSTOMI CORINNA , REMEN LUBOS , RICHARD-BILDSTEIN SYLVIA , SIFFERLEN THIERRY , WELLER THOMAS , MACDONALD DWIGHT , MCKAY DANIEL , POWELL DAVID A
- Assignee: ACTELION PHARMACEUTICALS LTD,BEZENCON OLIVIER,BOSS CHRISTOPH,BUR DANIEL,CORMINBOEUF OLIVIER,FISCHLI WALTER,GRISOSTOMI CORINNA,REMEN LUBOS,RICHARD-BILDSTEIN SYLVIA,SIFFERLEN THIERRY,WELLER THOMAS,MACDONALD DWIGHT,MCKAY DANIEL,POWELL DAVID A
- Current Assignee: ACTELION PHARMACEUTICALS LTD,BEZENCON OLIVIER,BOSS CHRISTOPH,BUR DANIEL,CORMINBOEUF OLIVIER,FISCHLI WALTER,GRISOSTOMI CORINNA,REMEN LUBOS,RICHARD-BILDSTEIN SYLVIA,SIFFERLEN THIERRY,WELLER THOMAS,MACDONALD DWIGHT,MCKAY DANIEL,POWELL DAVID A
- Priority: EP2004013610 2004-12-01
- Main IPC: C07D471/08
- IPC: C07D471/08 ; A61K31/4995 ; A61P13/12
Abstract:
The invention relates to novel bicyclic derivatives and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
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