Invention Application
WO2006136423A3 MEDICAMENT FOR THE TREATMENT OF IMPAIRED GLUCOSE METABOLISM 审中-公开
用于治疗有害葡萄糖代谢的药物

MEDICAMENT FOR THE TREATMENT OF IMPAIRED GLUCOSE METABOLISM
Abstract:
The present invention relares to compounds of the formula (I) wherein R 3 is C 1-6 -alkyloxy, C 1-6 -acyloxy or aroyloxy; R 6 is hydrogen or C 1-6 -alkyloxy; R 7 is C 1-6 -alkyloxy, C 1-6 -acyloxy, aroyloxy or arylacyloxy; R 8 is hydrogen or C 1-6 -alkyloxy; or R 7 and R 8 form together a group O-L-O with L being (CR 1 R 2 ) n , with R 1 and R 2 being independently from each other hydrogen or C 1-5 -alkyl and n being an interger from 1 to 3; R 10 is hydrogen or N-C 1-4 -acyl, N- C 1-5 -alkyl-x-C x -alkyl with x being an interger from 1 to 5, for use as medicament for the treatment of a disorder connected to impaired glucose metabolism and impaired insulin action such as syndrome X and diabetes type 1,apd 2, especially for the treatment of (non-autoimmune) diabetes type 2. The invention also relates to food and pharmaceutical compositions containing these compounds.
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