Invention Application
- Patent Title: HYDRAZIDE CONJUGATES AS IMAGING AGENTS
- Patent Title (中): 氢化物作为成像剂
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Application No.: PCT/US2006/025298Application Date: 2006-06-28
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Publication No.: WO2007005491A1Publication Date: 2007-01-11
- Inventor: HARRIS, Thomas, D. , ROBINSON, Simon, P. , CESATI, Richard, R. , YALAMANCHILI, Padmaja
- Applicant: BRISTOL-MYERS SQUIBB PHARMA COMPANY , HARRIS, Thomas, D. , ROBINSON, Simon, P. , CESATI, Richard, R. , YALAMANCHILI, Padmaja
- Applicant Address: Route 206 And Province Line Road, Princeton, New Jersey 08543-4000 US
- Assignee: BRISTOL-MYERS SQUIBB PHARMA COMPANY,HARRIS, Thomas, D.,ROBINSON, Simon, P.,CESATI, Richard, R.,YALAMANCHILI, Padmaja
- Current Assignee: BRISTOL-MYERS SQUIBB PHARMA COMPANY,HARRIS, Thomas, D.,ROBINSON, Simon, P.,CESATI, Richard, R.,YALAMANCHILI, Padmaja
- Current Assignee Address: Route 206 And Province Line Road, Princeton, New Jersey 08543-4000 US
- Agency: MINGO, Pamela A., Ph. D. et al.
- Priority: US60/695,496 20050630
- Main IPC: A61K51/08
- IPC: A61K51/08 ; A61K49/00 ; C07K1/13
Abstract:
The present disclosure is directed to diagnostic agents. More specifically, the disclosure is directed to compounds, diagnostic agents, compositions, and kits for detecting and/or imaging and/or monitoring a pathological disorder associated with coronary plaque, carotid plaque, aortic plaque, plaque of the arterial vessel, aneurism, vasculitis, and other diseases of the arterial wall. In addition, the disclosure is directed to methods of detecting and/or imaging and/or monitoring changes in the arterial wall, including expansive and constrictive remodeling, total vessel wall area, internal lumen size, and exterior artery perimeter.
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