发明申请
WO2007016202A1 USE OF A PKC ACTIVATOR, ALONE OR COMBINED WITH A PKC INHIBITOR TO ENHANCE LONG TERM MEMORY
审中-公开
使用PKC激活剂,单独或与PKC抑制剂组合以增强长期记忆
- 专利标题: USE OF A PKC ACTIVATOR, ALONE OR COMBINED WITH A PKC INHIBITOR TO ENHANCE LONG TERM MEMORY
- 专利标题(中): 使用PKC激活剂,单独或与PKC抑制剂组合以增强长期记忆
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申请号: PCT/US2006/029110申请日: 2006-07-28
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公开(公告)号: WO2007016202A1公开(公告)日: 2007-02-08
- 发明人: ALKON, Daniel, L.
- 申请人: BLANCHETTE ROCKEFELLER NEUROSCIENCES INSTITUTE , ALKON, Daniel, L.
- 申请人地址: One Medical Center Drive, P.O. Box 9301, Morgantown, WV 26596-9301 US
- 专利权人: BLANCHETTE ROCKEFELLER NEUROSCIENCES INSTITUTE,ALKON, Daniel, L.
- 当前专利权人: BLANCHETTE ROCKEFELLER NEUROSCIENCES INSTITUTE,ALKON, Daniel, L.
- 当前专利权人地址: One Medical Center Drive, P.O. Box 9301, Morgantown, WV 26596-9301 US
- 代理机构: STOLE, Einar
- 优先权: US60/703,501 20050729; US60/728,753 20051021
- 主分类号: A61K31/366
- IPC分类号: A61K31/366 ; A61K31/4015 ; A61P25/28
摘要:
The present invention provides methods of contacting a protein kinase C (PKC) activator with a PKC activator in a manner sufficient to stimulate the synthesis of proteins sufficient to consolidate long-term memory. The present invention also provides methods of contacting a protein kinase C (PKC) activator with a PKC activator in a manner sufficient to downregulate PKC.