Invention Application
WO2007029155A3 AN IMPROVED PROCESS FOR PREPARATION OF PURE CELIPROLOL BASE
审中-公开
用于制备纯CELIPROLOL基的改进方法
- Patent Title: AN IMPROVED PROCESS FOR PREPARATION OF PURE CELIPROLOL BASE
- Patent Title (中): 用于制备纯CELIPROLOL基的改进方法
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Application No.: PCT/IB2006053073Application Date: 2006-09-01
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Publication No.: WO2007029155A3Publication Date: 2007-08-30
- Inventor: KUMAR NARESH , NAYYAR SANDEEP , MAHENDRU MANU
- Applicant: RANBAXY LAB LTD , KUMAR NARESH , NAYYAR SANDEEP , MAHENDRU MANU
- Assignee: RANBAXY LAB LTD,KUMAR NARESH,NAYYAR SANDEEP,MAHENDRU MANU
- Current Assignee: RANBAXY LAB LTD,KUMAR NARESH,NAYYAR SANDEEP,MAHENDRU MANU
- Priority: IN2360DE2005 2005-09-05
- Main IPC: C07C273/18
- IPC: C07C273/18 ; C07C275/42
Abstract:
The present invention relates to an improved process for preparing pure celiprolol base in monohydrate form by crystallizing crude celiprolol base in one or more carboxylic acid ester solvents and its conversion to pharmaceutically acceptable acid addition salts, for example, celiprolol hydrochloride Form I in high purity.
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