发明申请
- 专利标题: TARGETED BIOCIDES
- 专利标题(中): 目标生物
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申请号: PCT/US2006/039361申请日: 2006-10-10
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公开(公告)号: WO2007047189A2公开(公告)日: 2007-04-26
- 发明人: IMBODEN, Michael , RIGGS, Michael, W. , SCHAEFER, Deborah
- 申请人: IOGENETICS, LLC , IMBODEN, Michael , RIGGS, Michael, W. , SCHAEFER, Deborah
- 申请人地址: 3591 Anderson Street, Suite 218, Madison, WI 53704 US
- 专利权人: IOGENETICS, LLC,IMBODEN, Michael,RIGGS, Michael, W.,SCHAEFER, Deborah
- 当前专利权人: IOGENETICS, LLC,IMBODEN, Michael,RIGGS, Michael, W.,SCHAEFER, Deborah
- 当前专利权人地址: 3591 Anderson Street, Suite 218, Madison, WI 53704 US
- 代理机构: ARENSON, Tanya, A. et al.
- 优先权: US60/725,180 20051011
- 主分类号: A61K39/40
- IPC分类号: A61K39/40 ; C07K16/12
摘要:
The present invention relates to retroviral constructs that encode novel monoclonal antibodies, novel fusion proteins, and chimeric monoclonal antibodies and to methods of using and producing the same. In particular, the present invention relates to methods of producing a fusion protein comprising a microorganism targeting molecule ( e.g., immunoglobulin or innate immune system receptor molecule) and a biocide ( e.g ., bactericidal enzyme) in transgenic animals ( e.g., bovines) and in cell cultures. The present invention also relates to therapeutic and prophylactic methods of using a fusion protein comprising a microorganism targeting molecule and a biocide in health care ( e.g ., human and veterinary), agriculture ( e.g., animal and plant production), and food processing ( e.g., beef carcass processing). The present invention also relates to methods of using a fusion protein comprising a microorganism targeting molecule and a biocide in various diagnostic applications in number of diverse fields such as agriculture, medicine, and national defense.