Invention Application
WO2007048802A1 (HETERO)ARYL COMPOUNDS WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS
审中-公开
（HETERO）ARYL化合物与MCH拮抗活性和药物包含这些化合物
- Patent Title: (HETERO)ARYL COMPOUNDS WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS
- Patent Title (中): （HETERO）ARYL化合物与MCH拮抗活性和药物包含这些化合物
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Application No.: PCT/EP2006/067750Application Date: 2006-10-25
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Publication No.: WO2007048802A1Publication Date: 2007-05-03
- Inventor: ROTH, Gerald Juergen , MUELLER, Stephan Georg , LEHMANN-LINTZ, Thorsten , STENKAMP, Dirk , LUSTENBERGER, Philipp , KLEY, Joerg , RUDOLF, Klaus , HECKEL, Armin , SCHINDLER, Marcus , THOMAS, Leo , LOTZ, Ralf R. H.
- Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH , BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG , ROTH, Gerald Juergen , MUELLER, Stephan Georg , LEHMANN-LINTZ, Thorsten , STENKAMP, Dirk , LUSTENBERGER, Philipp , KLEY, Joerg , RUDOLF, Klaus , HECKEL, Armin , SCHINDLER, Marcus , THOMAS, Leo , LOTZ, Ralf R. H.
- Applicant Address: Binger Str. 173, 55216 Ingelheim am Rhein DE
- Assignee: BOEHRINGER INGELHEIM INTERNATIONAL GMBH,BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG,ROTH, Gerald Juergen,MUELLER, Stephan Georg,LEHMANN-LINTZ, Thorsten,STENKAMP, Dirk,LUSTENBERGER, Philipp,KLEY, Joerg,RUDOLF, Klaus,HECKEL, Armin,SCHINDLER, Marcus,THOMAS, Leo,LOTZ, Ralf R. H.
- Current Assignee: BOEHRINGER INGELHEIM INTERNATIONAL GMBH,BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG,ROTH, Gerald Juergen,MUELLER, Stephan Georg,LEHMANN-LINTZ, Thorsten,STENKAMP, Dirk,LUSTENBERGER, Philipp,KLEY, Joerg,RUDOLF, Klaus,HECKEL, Armin,SCHINDLER, Marcus,THOMAS, Leo,LOTZ, Ralf R. H.
- Current Assignee Address: Binger Str. 173, 55216 Ingelheim am Rhein DE
- Agency: HAMMANN, Heinz et al.
- Priority: EP05110014.7 20051026
- Main IPC: C07D237/08
- IPC: C07D237/08 ; A61K31/501 ; A61P3/04
Abstract:
The present invention relates to (hetero)aryl compounds of general formula (I) wherein the groups and radicals A, B, Q, W, X, Y, Z, R 1 , R 2 , R 4a , R 4b , R 5a , R 5b , have the meanings given in claim 1. Moreover the invention relates to pharmaceutical compositions containing at least one compound according to the invention. By virtue of their MCH-receptor antagonistic activity the pharmaceutical compositions according to 10 the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia and diabetes.
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