Invention Application
WO2007107775A3 PREPARATION OF OLIGONUCLEOTIDES WITH PHOTOSWITCHABLE PROPERTIES 审中-公开
具有光电性质的寡核苷酸的制备

PREPARATION OF OLIGONUCLEOTIDES WITH PHOTOSWITCHABLE PROPERTIES
Abstract:
Linkers which provide for the attachment of photoswitchable compounds to nucleic acid are provided. These linkers can be used to provide photo-modulatable compounds wherein the chemical and biological properties of polynucleic acid incorporating these photo-modulatable compounds can be modulated by light. Further, methods for modulation of hybridisation of polynucleic acid sequences and binding of factors, for example polymerases to polynucleic acid sequences incorporating said photo-modulatable compounds are provided.
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