Invention Application
- Patent Title: PREPARATION OF OLIGONUCLEOTIDES WITH PHOTOSWITCHABLE PROPERTIES
- Patent Title (中): 具有光电性质的寡核苷酸的制备
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Application No.: PCT/GB2007001056Application Date: 2007-03-23
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Publication No.: WO2007107775A3Publication Date: 2008-03-27
- Inventor: VYLE JOSEPH S , TUCKER JAMES ROBERT
- Applicant: UNIV BELFAST , VYLE JOSEPH S , TUCKER JAMES ROBERT
- Assignee: UNIV BELFAST,VYLE JOSEPH S,TUCKER JAMES ROBERT
- Current Assignee: UNIV BELFAST,VYLE JOSEPH S,TUCKER JAMES ROBERT
- Priority: GB0605787 2006-03-23
- Main IPC: C07H21/00
- IPC: C07H21/00 ; C12N15/11 ; C12N15/113 ; C12Q1/68
Abstract:
Linkers which provide for the attachment of photoswitchable compounds to nucleic acid are provided. These linkers can be used to provide photo-modulatable compounds wherein the chemical and biological properties of polynucleic acid incorporating these photo-modulatable compounds can be modulated by light. Further, methods for modulation of hybridisation of polynucleic acid sequences and binding of factors, for example polymerases to polynucleic acid sequences incorporating said photo-modulatable compounds are provided.
Public/Granted literature
- WO2007107775A8 PREPARATION OF OLIGONUCLEOTIDES WITH PHOTOSWITCHABLE PROPERTIES Public/Granted day:2009-07-16
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