Invention Application
- Patent Title: CHEMICAL COMPOUNDS
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Application No.: PCT/US2007/017282Application Date: 2007-08-01
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Publication No.: WO2008016692A2Publication Date: 2008-02-07
- Inventor: EVINDAR, Ghotas , DENG, Hongfeng , BERNIER, Sylvie , YAO, Gang , COFFIN, Aaron , YANG, Hongfang
- Applicant: PRAECIS PHARMACEUTICALS INCORPORATED , EVINDAR, Ghotas , DENG, Hongfeng , BERNIER, Sylvie , YAO, Gang , COFFIN, Aaron , YANG, Hongfang
- Applicant Address: 830 Winter Street Waltham, MA 02451-1420 US
- Assignee: PRAECIS PHARMACEUTICALS INCORPORATED,EVINDAR, Ghotas,DENG, Hongfeng,BERNIER, Sylvie,YAO, Gang,COFFIN, Aaron,YANG, Hongfang
- Current Assignee: PRAECIS PHARMACEUTICALS INCORPORATED,EVINDAR, Ghotas,DENG, Hongfeng,BERNIER, Sylvie,YAO, Gang,COFFIN, Aaron,YANG, Hongfang
- Current Assignee Address: 830 Winter Street Waltham, MA 02451-1420 US
- Agency: DECONTI, Giulio, A. et al.
- Priority: US60/821,101 20060801; US60/827,919 20061003; US60/896,431 20070322; US60/959,291 20070712
- Main IPC: C07D213/38
- IPC: C07D213/38 ; C07D239/26 ; C07D261/08 ; C07D271/10 ; C07D277/28 ; C07D285/12 ; C07D417/12 ; C07F9/6539 ; A61K31/425 ; A61K31/433 ; A61K31/44 ; A61K31/505 ; A61P37/00
Abstract:
The invention provides compounds formula I, their preparation, and their use as pharmaceutically active immunosuppressive agents for the treatment of autoimmune disorders, organ transplant rejection, disorders associated with an activated immune system, as well as other disorders modulated by lymphopenia or SlP receptors.
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